How to Manage Treatment of Hypothyroidism in Patients with Cardiac Disease

Highlights Autoantibodies refine autoimmune thyroid disorder diagnosis and risk. Thyroid-stimulating hormone receptor antibody predicts relapse, severity and foetal impact. Thyroid peroxidase antibody and thyroglobulin antibody linked to fertility outcomes. Novel antibodies expand thyroid autoimmunity scope. The interplay between immunology and ...

Welcome to the latest edition of touchREVIEWS in Endocrinology, which features a diverse selection of editorials, reviews and original research articles that highlight both the progress and the ongoing challenges in translating pathophysiological insight into patient-centred care. We begin with ...

Thyroid eye disease (TED), also known as Graves’ orbitopathy, is a complex autoimmune disorder driven by an interplay of immune cells, orbital fibroblasts and tissue remodelling factors that lead to inflammation, oedema and, ultimately, potential vision loss.1 While the disease ...

It is with great pleasure that we present this latest issue of touchREVIEWS in Endocrinology, which brings together a diverse array of high-quality articles focused on the evolving landscape of endocrine disorders. The importance of patient-centred care is exemplified in ...

This systematic review and meta-analysis investigate the efficacy of teprotumumab, a novel monoclonal antibody, in reducing proptosis for patients with long-duration thyroid eye disease (TED). While teprotumumab has shown promise in treating active TED, its effectiveness in chronic cases remained ...

Hypercalcaemia is a common clinical condition in hospitalized patients. Malignancies and primary hyperparathyroidism (PHPT) are the two most common causes of hypercalcaemia in hospitalized patients.1–3 Apparently, there is a changing profile of hypercalcaemia in India, especially in hospital settings, because ...

Hyperthyroidism is prevalent in 0.1–2.5% of the population, and Graves’ disease is diagnosed in 80% of patients with hyperthyroidism.1,2 This condition arises from the uncontrolled, excessive activation of the thyroid-stimulating hormone (TSH) receptor by autoreactive TSH-receptor antibodies.2 Elevated thyroid hormones in hyperthyroidism ...

Thyroid nodules are common worldwide, and their prevalence is increasing. Most nodules are asymptomatic and detected incidentally on cross-sectional imaging or physical examination. In rare cases (10–15%), nodules are malignant and require diagnostic evaluation. Even malignant nodules frequently show non-aggressive behaviour.1 ...

Welcome to the latest edition of touchREVIEWS in Endocrinology, which features a range of review, case report and original research articles that highlight some key developments in our understanding and management of endocrinological disease. We begin with a commentary from ...

Amyloid goiter (AG) is a benign condition characterized by the deposition of amorphous proteinaceous material in the thyroid gland to an extent that results in detectable enlargement during clinical evaluation.1–3 Amyloid can infiltrate the thyroid gland in 15–50% of individuals with ...

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In the USA, neck ultrasound (US) identifies thyroid nodules (TNs) in 30–50% of adult patients.1,2 Given that the risk of malignancy (ROM) for all combined thyroid nodule types ranges from 5% to 15%,2,3 current guidelines recommend US of the neck initially, to identify ...