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Saptarshi Bhattacharya, Sanjay Kalra, Lakshmi Nagendra

Very few trials in the history of medical science have altered the treatment landscape as profoundly as the UK Prospective Diabetes Study (UKPDS). Even 44 years after its inception, the trial and post-study follow-up findings continue to fascinate and enlighten the medical community. The study was conceived at a time when there was uncertainty about […]

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The Dhaka Declaration— Bringing Gestational Diabetes Mellitus (GDM) to Center Stage

Faruque Pathan, Sarita Bajaj, Dina Shrestha, Syed Abbas Raza, Noel Somasundaram, Tofail Ahmed, Sanjay Kalra
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Published Online: Oct 29th 2015 US Endocrinology, 2015;11(2):81–2 DOI: http://doi.org/10.17925/USE.2015.11.02.81
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Abstract

Overview

This special report covers The Dhaka Declaration, an initiative of the five-nation South Asian Federation of Endocrine Societies (SAFES). Involving Bangladesh, India, Nepal, Pakistan, and Sri Lanka, this endocrine association aims to bring gestational diabetes mellitus (GDM) to the center stage of clinical medicine as well as public health. The Dhaka Declaration provides guidance for advocacy, research, and guideline formation in the field of GDM. Through these activities, SAFES hopes to bring about universal screening, uniformity in diagnosis, optimal management, and regular follow-up of GDM.

Keywords

Advocacy, diabetes, GDM pre- and postnatal management, guideline formation for GDM, pregnancy, research, screening

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Article

South Asia—Diabetes Capital
South Asia is known as the Diabetes Capital of the World, and justifiably so. Home to three of the world’s largest populations of people living with diabetes (India, Bangladesh, and Pakistan), it also includes nations with an equally high prevalence of diabetes (Bhutan, Maldives, Nepal, and Sri Lanka). With diabetes having entrenched itself in the South Asian populace, it is now considered an endemic, rather than an epidemic.1

Gestational Diabetes Mellitus
Epidemics of disease usually require interventions that are designed to show rapid control that may be short term. Endemics, on the other hand, need long-term measures that help contain the illness and lead to longlasting benefit as well.

It is in this context that the five-nation South Asian Federation of Endocrine Societies (SAFES) released The Dhaka Declaration in April 2015. Led by Professor Hajera Mahtab of Bangladesh, experts from Sri Lanka, Pakistan, Nepal, India, and Bangladesh identified gestational diabetes mellitus (GDM) as a focus area for the coming 2 years.2

The Dhaka Declaration—From Thoughts to Words
GDM was chosen because of its public health importance,3 the opportunity it provides for interspecialty and interprofessional collaboration, and the availability of evidence-backed nonpharmacologic and pharmacologic interventions that can favorably impact health-related outcomes.4 Most importantly, GDM was identified to have a transgenerational influence on health, affecting not only the woman with GDM, during and after pregnancy, but also the offspring, in utero, in infancy, and later in adult life as well.

The Dhaka Declaration lists various aims and describes the activities to be conducted across all South Asian countries. In the declaration, SAFES resolves to facilitate universal screening, uniformity in diagnosis, and optimal management and follow-up of GDM, including appropriate usage of insulin. It also proposes indicators or markers to assess progress in this field.

From Words to Action
Six months after the Dhaka Declaration was released, SAFES met again to plan a course of action. At a meeting held on October 1, 2015, in Colombo, Sri Lanka, 30 participants shared a situational analysis of GDM in their home countries and prepared a research map to help identify missing gaps in knowledge related to GDM. The South Asian girl child was at the center stage. Focused group discussions on preconception management, screening, and antenatal management, as well as postpartum follow-up, were held. Emphasis was laid on creating a research-friendly environment and facilitating pan-South Asian research in an inclusive manner. Four task forces, dealing with Advocacy, Research, Guideline writing, and Practice Patterns and Public awareness, were formed, including representatives from each South Asian country. The Advocacy Taskforce for GDM will aim to sensitize all stakeholders, including governments, about the need to focus on GDM prevention and management as a means of preventing diabetes and containing the diabetes endemic in current as well as future generations. It will also take the lead in involving other medical specialties and health professions in the fight against GDM. The Research Taskforce will prepare blueprints and protocols for large-scale trials on GDM. South Asian research is required to answer questions that currently have no simple solution. Randomized controlled trials are being planned to identify the best method of GDM screening and postpartum screening. Studies will also be conducted to assess current practice related to GDM management across South Asia. The Guideline writing Taskforce will encapsulate available evidence to prepare pragmatic suggestions. Guidelines of international quality, appropriate to the South Asian population and health care system, will be drafted and published. Current practice trends among South Asian physicians will be assessed by meansof a questionnaire. Public education targeting schools and colleges with education material and talks on noncommunicable disease, with GDM as the fulcrum, will be supported.

South Asia—The Diabetes Care Capital
The Dhaka Declaration, building upon earlier multinational South Asian initiatives,5 has created an optimistic atmosphere of proactive collaboration in South Asia endocrinology circles. With various activities planned, more and more clinicians, researchers, and policymakers are being involved in the management and follow-up of GDM. Through successful implementation of The Dhaka Declaration, SAFES hopes to improve the quality of care provided to women with GDM, improve diabetes care in general, and help contain the diabetes endemic.

The Dhaka Declaration is a means to focus our collective energy and strength, to create synergy and teamwork, and to achieve a common goal: to ensure that South Asia gets recognized not as the diabetes capital, but as the diabetes CARE capital, of the world.

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References

1. Kalra S, Kumar A, Jarhyan P, Unnikrishnan AG, Endemic or epidemic? Measuring the endemicity index of diabetes, Indian J Endocrinol Metab, 2015;19:5–7.
2. Mahtab H, Pathan M, Ahmed T, et al., The Dhaka declaration 2015, Indian J Endocrinol Metab, 2015;19:441–2.
3. Kalra S, Gupta Y, Post-partum screening of gestational diabetes: opportunities for integration with existing public health, Indian J Community Med, 2015;40:209–10.
4. Tandon N, Gupta Y, Kalra S, Postpartum screening after gestational diabetes mellitus: aiming for universal coverage, Indian J Endocrinol Metab, 2015;19:1–4.
5. Bajaj S, Jawad F, Islam N, et al., South Asian women with diabetes: psychosocial challenges and management: Consensus statement, Indian J Endocrinol Metab, 2013;17:548–62.

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Article Information

Disclosure

Faruque Pathan, Sarita Bajaj, Dina Shrestha, Syed Abbas Raza, Noel Somasundaram, Tofail Ahmed, Rakesh Sahay, and Sanjay Kalra have no conflicts of interest to
disclose. No funding was received for the publication of this article.

Correspondence

Sanjay Kalra, MD, DM, Department of Endocrinology, Bharti Hospital, Karnal, India. E: brideknl@gmail.com

Access

This article is published under the Creative Commons Attribution Noncommercial License, which permits any noncommercial use, distribution, adaptation, and
reproduction provided the original author(s) and source are given appropriate credit.

Received

2015-10-14T00:00:00

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