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Hyperprolactinemia is a frequent cause for medical referrals to endocrinology departments. Markedly elevated prolactin levels are generally indicative of macroprolactinomas, whereas mild to moderate hyperprolactinemia may arise from physiological factors (such as exercise, sleep or stress), pharmacological agents, metabolic disturbances, untreated primary hypothyroidism, as well as hypothalamic–pituitary disorders, including microprolactinomas or pituitary stalk compression due to […]

Osama Hamdy, ADA 2022: Tirzepatide for obesity in the SURMOUNT-1 study and remission in type 2 diabetes

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Published Online: Jul 19th 2022

The results of SURMOUNT-1, the first phase 3 trial with the novel GIP/GLP-1 receptor agonist tirzepatide for obesity, is discussed by Dr Osama Hamdy (Joslin Diabetes Center, Boston, MA, USA) as well as key data on remission, a key theme at the 82nd American Diabetes Association Scientific Session, June 3-7, 2022.

Questions: 

  1. What were the key clinical trial highlights presented at the 82nd ADA meeting? (0:23)
  2. The topline results of the groundbreaking SURMOUNT-1 study were presented at this year’s meeting. What are the potential implications of these findings for treating obesity, prediabetes, and type 2 diabetes? (1:53)
  3. Remission was an important theme at this year’s meeting, can you highlight the key presentations discussing remission in type 2 diabetes and their findings? (3:43)

Disclosures: Osama Hamdy is a consultant for Abbott Nutrition and Sanofi Aventis, has received grant/research support from Eli Lilly, National Dairy Council and Novo-Nordisk. Osama Hamdy is on the advisory Board for L-Neutra, Nemaura and Twin Health and is a major stock shareholder in Healthimation Inc.

Support: Interview and filming supported by Touch Medical Media. Interview conducted by Danielle Crosby.

Filmed as a highlight of ADA 2022.

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