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Saptarshi Bhattacharya, Sanjay Kalra, Lakshmi Nagendra

Very few trials in the history of medical science have altered the treatment landscape as profoundly as the UK Prospective Diabetes Study (UKPDS). Even 44 years after its inception, the trial and post-study follow-up findings continue to fascinate and enlighten the medical community. The study was conceived at a time when there was uncertainty about […]

Osama Hamdy, ADA 2022: Tirzepatide for obesity in the SURMOUNT-1 study and remission in type 2 diabetes

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Published Online: Jul 19th 2022

The results of SURMOUNT-1, the first phase 3 trial with the novel GIP/GLP-1 receptor agonist tirzepatide for obesity, is discussed by Dr Osama Hamdy (Joslin Diabetes Center, Boston, MA, USA) as well as key data on remission, a key theme at the 82nd American Diabetes Association Scientific Session, June 3-7, 2022.

Questions: 

  1. What were the key clinical trial highlights presented at the 82nd ADA meeting? (0:23)
  2. The topline results of the groundbreaking SURMOUNT-1 study were presented at this year’s meeting. What are the potential implications of these findings for treating obesity, prediabetes, and type 2 diabetes? (1:53)
  3. Remission was an important theme at this year’s meeting, can you highlight the key presentations discussing remission in type 2 diabetes and their findings? (3:43)

Disclosures: Osama Hamdy is a consultant for Abbott Nutrition and Sanofi Aventis, has received grant/research support from Eli Lilly, National Dairy Council and Novo-Nordisk. Osama Hamdy is on the advisory Board for L-Neutra, Nemaura and Twin Health and is a major stock shareholder in Healthimation Inc.

Support: Interview and filming supported by Touch Medical Media. Interview conducted by Danielle Crosby.

Filmed as a highlight of ADA 2022.

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