The prevalence of obesity is increasing worldwide and along with it the economic burden of obesity-related complications. Several pharmacotherapies have been approved to, suppress appetite and reduce lipid absorption, although lifestyle and behavioural changes remain the mainstay of the treatment paradigm. Research into SGLT-2 inhibitors, amylin mimetics, leptin analogues and ghrelin antagonists as potential treatments are ongoing.
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As we continue advancing the field of endocrinology, I’m excited to spotlight the impactful work being done by the American Association of Clinical Endocrinology (AACE). Our mission is to elevate the practice of clinical endocrinology to improve global health. ...
The potential future role of GLP-1–based combinations in the management of obesity with or without diabetes.
The 3-year results from the SURMOUNT-1 trial, published in the New England Journal of Medicine, have revealed that tirzepatide significantly reduced the risk of progression to type 2 diabetes (T2D) in individuals with obesity and prediabetes. T2D onset was ...
Watch a leading expert discuss the need for personalised obesity treatment including current evidence for cardiovascular outcomes.
In this expert Q&A we are delighted to welcome our Editorial Board member Dr Sanjay Kalra, a leading endocrinologist with over two decades of experience at Bharti Hospital, Karnal, India. A passionate educator and researcher, Dr Kalra serves as Education Editor of the International Society of Endocrinology (ISE) and is deeply involved in global endocrine education. His leadership extends to roles such as Immediate Past President of the Endocrine Society of India and Vice-President of the South Asian Federation of Endocrine Societies.
We're excited to introduce a new series of expert Q&As featuring members of the touchREVIEWS in Endocrinology editorial board and faculty. In this series, they will share key career milestones, offer valuable advice for aspiring future leaders, and provide forward-looking insights into their areas of expertise.
Tirzepatide is a first-in-class novel dual glucose-dependent insulinotropic peptide (GIP)/glucagon-like peptide-1 (GLP-1) receptor agonist (twincretin), formulated as a synthetic peptide containing 39 amino acids based on the native GIP.1Â Tirzepatide has a GIP receptor-binding affinity comparable with native GIP and ...
Welcome to the latest edition of touchREVIEWS in Endocrinology, which features a range of review, case report and original research articles that highlight some key developments in our understanding and management of endocrinological disease. We begin with a commentary from ...
Obesity defined as abnormal or excessive fat accumulation that presents a risk to health, is a chronic disease linked to metabolic co-morbidities, such as type 2 diabetes mellitus and cardiovascular disease, a reduced life expectancy, economic burden and reduced quality of ...
Periodontitis is a chronic inflammatory disease of the periodontium, or the supportive tissues around the tooth, which includes the gingival tissue, alveolar bone, cementum and the periodontal ligament.1Â Caused by pathogenic bacteria, this disease has been recognized for at least 5,000 ...
Obesity is related to an increased risk of metabolic disease.1Â It is well established that excessive body fat is related to increased morbidity and mortality and is associated with inflammation and endothelial damage.2,3Â With age, fat infiltration occurs in the ...
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