US Endocrinology – Volume 15 Issue 1 – Summer 2019

Welcome to the spring edition of US Endocrinology. We aim to address topical subjects in the field to stimulate discussion focused on these issues. Articles have been chosen for their evaluation of current practices and research and their discussion of future innovations that directly affect endocrinologists and other healthcare professionals. The journal opens with a series […]

About The American Association of Diabetes Educators The American Association of Diabetes Educators (AADE) is an interdisciplinary professional membership organization dedicated to improving prediabetes, diabetes, and cardiometabolic care through innovative education, management, and support. With more than 14,000 professional members including nurses, dietitians, pharmacists, exercise specialists, and others, AADE has a vast network of practitioners […]

A significant proportion of healthcare providers, especially those engaged in diabetes care, display features of physician burnout and/or compassion fatigue at some time. Development of compassion fatigue can not only affect the provider–patient relationship and patient outcomes, it can also be detrimental to the professional and personal wellbeing of the diabetes care practitioner. In an […]

Type 1 diabetes (T1D) is an autoimmune disease characterized by the dysfunction and/or destruction of the insulin-producing beta cells found in the pancreatic islets of Langerhans.1 New insights into the course of T1D have led to the realization that the disease progresses through distinct stages prior to the onset of symptoms, and the development of […]

Understanding the mechanisms that regulate beta cell development and function is crucial to identify therapeutic targets in type 1 and type 2 diabetes. One way to find the genes or factors needed for beta cells is to study the genetics of patients who develop diabetes in the first few months of life because of severe […]

Various prandial insulins, including regular human insulin, aspart, glulisine, lispro and fast-acting insulin aspart (FIAsp), are used as part of basal plus, basal bolus, or prandial alone regimens. Some prandial insulins, also known as short-acting insulins, can also be used intravenously, or in insulin infusion pumps. The focus of this editorial is to classify prandial […]

Heart failure (HF) is a disease that affects about 10% of men and 8% of women over the age of 60 years, and its prevalence increases with age.1 HF and type 2 diabetes are each characterized by insulin resistance and are accompanied by the activation of neurohormonal systems; 35–45% of patients with HF have diabetes.2 HF is […]

The clinical connection between metabolic health and vascular disease is well-known.1–4 While an association between obesity and diabetes has been historically described, the past century has witnessed the evolution of broader understanding in vasculo-metabolic health.1–4 In 1923, the Swedish physician Kylin described an association between hypertension, hyperglycemia, and gout.5 Since then, several developments progressively led to the recognition […]

Palpation and physical exam remain an important part of thyroid evaluation, and while nodular discovery has increased overall, the prevalence of palpable thyroid nodules has not changed significantly since the 1960s, and remains around 3–7%.1–5 Currently, ultrasonography of the neck area has incidentally identified thyroid nodules with an incidence of 30–70 %,6,7 and unrelated computerized tomography (CT) […]

Liquid biopsy is a rapidly emerging technique that measures extracellular DNA in a patient’s blood and is of considerable interest as a non-invasive method for early recognition and management of cancer.1,2 Circulating cell-free DNA (cfDNA) fragments in the blood are present at low levels in healthy individuals and at higher levels in patients with clinical disorders […]