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We are pleased to present the latest issue of touchREVIEWS in Endocrinology, which offers a timely and thoughtprovoking collection of articles that reflect both the continuity and evolution of diabetes and metabolic disease research. In an era where technology, public health priorities and clinical paradigms are shifting rapidly, this issue highlights the importance of evidence-based […]

US ENDOCRINE REVIEW – VOLUME 1 – SUMMER 2005

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1

Foreword

3 mins
Nathaniel G Clarke

The successful treatment of diabetes depends on the education of the patient to manage their own diabetes, and is therefore considered the cornerstone of the treatment plan. Essentially, the success that patients gain in treating their diabetes stems from their ability to learn and appropriately practice self-care. While healthcare providers see patients only episodically, usually […]

2

Current Issues

Dietary supplements are defined by the US Dietary Supplement Health and Education Act (DSHEA) as a vitamin or mineral, a herb or other plant-derived chemical, an amino acid, a dietary supplement by increasing the total dietary intake (including enzymes or tissues from organs or glands), or a concentrate, metabolite, constituent, or extract of these.

3

Diabetes Management

Diabetes is a complex disease requiring the adoption of numerous skills and behaviors in order for the disease to be managed successfully. Diabetes education seeks to reach these goals: provide knowledge and skill training; facilitate problem-solving; help individuals identify barriers; motivate for lifestyle adaptation; and develop coping skills to achieve goals.

In a study examining the relative contribution of postprandial glucose and fasting glucose of the A1C, Monnier et al.4 found that fasting glucose was a much greater contributor when A1C was 8.4% and higher whereas postprandial glucose was more influential when A1C was below 8.4%. From a practical perspective, this finding may provide some guidance […]

4

Diabetes & Cardiovascular Risk

However, statin-based interventions are unlikely to correct problems of triglycerides and HDL, whereas the use of fibrates has a stronger effect on the atherogenic dyslipidemia and might even produce significant LDL reduction in some patients.

MS is closely associated with obesity, which has shown a disturbing increase in prevalence, both in the US and worldwide, creating an unprecedented risk for CV disease (CVD). Obesity is prevalent across all demographic groups and is non-gender-specific.Nearly two-thirds of all adult Americans are now considered overweight or obese. Obesity is also rampant in children […]

It is generally thought that about 30% of the population with diabetes remains undiagnosed in industrialized nations, whereas the impact of diabetes is considerably less in developing countries because people die young due to malnutrition and infectious diseases. Nonetheless, the financial burden is too great for treating diabetes-induced complications such as heart attack, stroke, blindness, […]

5

Diabetes & Chronic Kidney Disease

Diabetic nephropathy is the primary cause of renal failure in the US and most developed countries, accounting for over 40% of prevalent patients initiating dialysis in the US Endstage Renal Disease (ESRD) program. Pathologically, diabetic nephropathy is thought to have a similar histological presentation in both type 1 and type 2 diabetic patients, although less […]

6

Diabetic Neuropathy

As a result of conducting research and reviewing published studies from around the world, new models concerning the causes of neuropathy have been discovered. What is needed is a fuller understanding of the etiology of the condition so that new technology can be brought to bear with both ameliorative and therapeutic benefits. This article offers […]

In diabetes, several specific pathologies contribute to the ulceration of the foot. Functional abnormalities of the microvasculature restrict the delivery of oxygen and other nutrients to the distal tissues of the extremities. The microvascular abnormalities include thickening of the capillary basement membrane,2 arteriovenous shunting,3 and a reduced vasodilatory capacity.4 These combined effects result in impaired […]

Diabetes remains the most common cause of neuropathy in the US, and neuropathy is the most common complication and greatest source of morbidity and mortality in diabetic patients. Additionally, emerging studies suggest that impaired glucose tolerance may lead to polyneuropathy, particularly painful small-fiber neuropathy. It is estimated from epidemiological studies that the prevalence of neuropathy […]

7

Pituitary Disorders

Example of myth: pituitary tumors are rare. Fact: these tumors are very common and can be detected in nearly 17.6% of the population (see description of meta-analysis below). Example: the tumor is so small, it is best to watch it and wait.

8

Thyroid Disorders

This capability has expanded the use of ultrasound and resulted in the development of new ultrasound applications for both the diagnosis and therapy of thyroid and parathyroid disorders. Ultrasound guidance for needle biopsy of thyroid nodules has become routine. It is now being used to confirm the ultrasound diagnosis of parathyroid adenoma by measuring parathyroid […]

9

Testosterone Replacement Therapy

Testosterone replacement is at the center of intense debate for its proper uses, its benefits, and its potential long-term side effects. With the growing number of US Food and Drug Administration (FDA)-approved methods for testosterone replacement in deficient men, particularly the aging male population, the subject has taken on growing importance that impacts every specialty. […]

10

Erectile Dysfunction

The goal of healthcare practitioners should be to provide their patients with optimal sexual healthcare through safe and effective evidence-based management strategies. For this reason, a holistic, multidimensional approach should be applied to each patient and his/her partner to address associated physical, mental, and social (or relationship) concerns.

11

Reference Section

In a study examining the relative contribution of postprandial glucose and fasting glucose of the A1C, Monnier et al.4 found that fasting glucose was a much greater contributor when A1C was 8.4% and higher whereas postprandial glucose was more influential when A1C was below 8.4%. From a practical perspective, this finding may provide some guidance […]

However, statin-based interventions are unlikely to correct problems of triglycerides and HDL, whereas the use of fibrates has a stronger effect on the atherogenic dyslipidemia and might even produce significant LDL reduction in some patients.

Diabetic nephropathy is the primary cause of renal failure in the US and most developed countries, accounting for over 40% of prevalent patients initiating dialysis in the US Endstage Renal Disease (ESRD) program. Pathologically, diabetic nephropathy is thought to have a similar histological presentation in both type 1 and type 2 diabetic patients, although less […]

Testosterone replacement is at the center of intense debate for its proper uses, its benefits, and its potential long-term side effects. With the growing number of US Food and Drug Administration (FDA)-approved methods for testosterone replacement in deficient men, particularly the aging male population, the subject has taken on growing importance that impacts every specialty. […]

Diabetes remains the most common cause of neuropathy in the US, and neuropathy is the most common complication and greatest source of morbidity and mortality in diabetic patients. Additionally, emerging studies suggest that impaired glucose tolerance may lead to polyneuropathy, particularly painful small-fiber neuropathy. It is estimated from epidemiological studies that the prevalence of neuropathy […]

As a result of conducting research and reviewing published studies from around the world, new models concerning the causes of neuropathy have been discovered. What is needed is a fuller understanding of the etiology of the condition so that new technology can be brought to bear with both ameliorative and therapeutic benefits. This article offers […]

The goal of healthcare practitioners should be to provide their patients with optimal sexual healthcare through safe and effective evidence-based management strategies. For this reason, a holistic, multidimensional approach should be applied to each patient and his/her partner to address associated physical, mental, and social (or relationship) concerns.

This capability has expanded the use of ultrasound and resulted in the development of new ultrasound applications for both the diagnosis and therapy of thyroid and parathyroid disorders. Ultrasound guidance for needle biopsy of thyroid nodules has become routine. It is now being used to confirm the ultrasound diagnosis of parathyroid adenoma by measuring parathyroid […]

12
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US Endocrinology is a peer-reviewed, free-to-access, bi-annual journal comprising review articles, case reports, editorials, special reports and original research. It features balanced and comprehensive articles written by leading authorities, addressing the most important and salient developments in the field of endocrinology.

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