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Thyroid gland inside human body. 3D illustration
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Thyroid eye disease (TED), also known as Graves’ orbitopathy, is a complex autoimmune disorder driven by an interplay of immune cells, orbital fibroblasts and tissue remodelling factors that lead to inflammation, oedema and, ultimately, potential vision loss.1 While the disease has historically been challenging to manage, recent therapeutic innovations are reshaping treatment paradigms and offering new […]

EUROPEAN ENDOCRINOLOGY VOLUME 13 ISSUE 1 – SPRING 2017

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1

Foreword

It is vital for all of us involved in endocrinology and diabetes to keep abreast of advances in the various fields which will help those for whom we are responsible, our patients. As an endocrinologist with a particular interest in endocrine oncology, I am aware that attending specialist meetings and workshops is to be at […]

2

Letter

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I am delighted to take on the role of Editor-in-Chief for European Endocrinology and would like to take this opportunity to introduce myself. I’m a National Institute for Health Research Clinician Scientist at the University of Birmingham and an Honorary Consultant Physician in Diabetes and Endocrinology and Obesity at Heart of England NHS Foundation Trust. […]

3

Interview

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Autoimmune destruction of pancreatic beta-cells results in absolute insulin deficiency, type 1 diabetes mellitus (T1DM). Insulin therapy is required for people with T1DM to achieve an optimal glycated haemoglobin (HbA1c or A1c) along with controlled dayto- day blood glucose (BG) levels. While a variety of insulin delivery systems are available, factors such as the complexity […]

4

Editorial

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In the last five years, we have witnessed significant progress in the management of obesity and associated metabolic disorders, including type 2 diabetes mellitus (T2DM). The evidence comes from well-controlled randomised controlled trials (RCTs) and has changed the management of these conditions in clinic. What we learned from the Action for Health in Diabetes (Look […]

It is highly appealing to manage osteoporosis and reduce risk of fracture by using drugs that can restore bone microarchitecture and bone strength; such drugs are bone anabolic agents. Teriparatide is the only currently licensed anabolic bone drug and has been used clinically for around 15 years,1 and has an important established, albeit narrow, position […]

5

Review

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The International Diabetes Federation (IDF) estimated that the total number of adults (20–79 years) living with diabetes in 2015 was 415 million and that by 2040, the number is predicted to rise to 642 million (see Figure 1).1 In countries with a low healthcare budget, biosynthetic human insulin is the mainstay of effective therapy, and […]

6

Original Research

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The incidence of thyroid cancer is increasing at a rate of 7% a year; there were an estimated 62,450 cases diagnosed in the US in 2015 alone. The majority of this rise in incidence is explained by the growing number of incidentally detected well-differentiated, early-stage or ‘low-risk’ papillary thyroid cancers (PTCs).3 There is a growing […]

7

Case Series

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Takotsubo cardiomyopathy (TC), frequently referred as stress-induced cardiopathy, apical ballooning syndrome or ‘broken heart’ syndrome, is characterised by left ventricular ballooning and transient systolic dysfunction. The Japanese term ‘takotsubo’ means a trap to catch an octopus, and its shape resembles this condition’s left ventricular systolic appearance.1 Clinically, TC can mimic an acute coronary syndrome (precordial […]

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touchREVIEWS in Endocrinology (previously European Endocrinology) is a peer-reviewed, free-to-access, bi-annual journal comprising review articles, case reports, editorials, special reports and original research. It features balanced and comprehensive articles written by leading authorities, addressing the most important and salient developments in the field of endocrinology.

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