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Saptarshi Bhattacharya, Sanjay Kalra, Lakshmi Nagendra

Very few trials in the history of medical science have altered the treatment landscape as profoundly as the UK Prospective Diabetes Study (UKPDS). Even 44 years after its inception, the trial and post-study follow-up findings continue to fascinate and enlighten the medical community. The study was conceived at a time when there was uncertainty about […]

Patrick Schrauwen PhD, ADA 2019 – Circadian Rhythmicity of Skeletal Muscle Metabolism

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Published Online: Jun 19th 2019

We are joined by Patrick Schrauwen at the ADA 2019 conference in San Francisco to discuss his symposium on circadian rhythmicity of skeletal muscle metabolism and its role in insulin resistance in humans, which is being presented at this year’s meeting.

Filmed at the American Diabetes Association (ADA) annual meeting 2019, San Francisco, USA.

Questions:
1. What was the rationale for studying the effect of circadian rhythm on skeletal muscle insulin sensitivity? (0:05)
2. What have we learned from these studies? (0:38)
3. What are the implications of this for whole-body insulin resistance? (1:17)
4. How can these findings be used to improve the management of shift workers with type 2 diabetes? (1:48)
5. What further studies are planned? (2:44)

Patrick Schrauwen has no conflicts of interest to declare in relation to this video.

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