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Hyponatraemia is primarily a disorder of water balance or distribution, characterized by serum sodium (Nas) levels less than 135 mmol/L.1 Hyponatraemia is the most common electrolyte disorder among elderly patients and is associated with increased mortality rates and longer hospital stays.2–4 The syndrome of inappropriate antidiuretic hormone secretion (SIADH) is a frequent cause of hyponatraemia in […]

Osama Hamdy, ADA 2022: Tirzepatide for obesity in the SURMOUNT-1 study and remission in type 2 diabetes

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Published Online: Jul 19th 2022

The results of SURMOUNT-1, the first phase 3 trial with the novel GIP/GLP-1 receptor agonist tirzepatide for obesity, is discussed by Dr Osama Hamdy (Joslin Diabetes Center, Boston, MA, USA) as well as key data on remission, a key theme at the 82nd American Diabetes Association Scientific Session, June 3-7, 2022.

Questions: 

  1. What were the key clinical trial highlights presented at the 82nd ADA meeting? (0:23)
  2. The topline results of the groundbreaking SURMOUNT-1 study were presented at this year’s meeting. What are the potential implications of these findings for treating obesity, prediabetes, and type 2 diabetes? (1:53)
  3. Remission was an important theme at this year’s meeting, can you highlight the key presentations discussing remission in type 2 diabetes and their findings? (3:43)

Disclosures: Osama Hamdy is a consultant for Abbott Nutrition and Sanofi Aventis, has received grant/research support from Eli Lilly, National Dairy Council and Novo-Nordisk. Osama Hamdy is on the advisory Board for L-Neutra, Nemaura and Twin Health and is a major stock shareholder in Healthimation Inc.

Support: Interview and filming supported by Touch Medical Media. Interview conducted by Danielle Crosby.

Filmed as a highlight of ADA 2022.

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