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Article highlights There is growing clinical importance attributed to the development of metabolic dysfunction-associated steatotic liver disease in people with type 2 diabetes (T2D). Numerous international groups now advocate screening for advanced fibrosis in people with risk factors, such as T2D, using non-invasive biomarkers. This article explores the rationale to screen for advanced fibrosis in people with risk […]

Hiddo Heerspink, ADA 2022: Current treatment options for chronic kidney disease in type 2 diabetes and the unmet needs

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Published Online: Jun 27th 2022

The current treatment options for chronic kidney disease in patients with type 2 diabetes is discussed by Professor Hiddo Heerspink (University Medical Center Groningen, Groningen, Netherlands). Also discussed is the mechanism of tirzepatide, a novel once-weekly medication, which has shown to improve kidney outcomes in adults with type 2 diabetes who have increased cardiovascular risk.

Professor Hiddo Heerspink presented an abstract entitled ‘Effects of Tirzepatide vs. Insulin Glargine 100 U/mL on Kidney Outcomes in Participants with Type 2 Diabetes in SURPASS-4‘ at the 82nd American Diabetes Association Scientific Session, June 3-7, 2022.

Questions: 

  1. Why is it so important to control the progression of chronic kidney disease (CKD) in people with type 2 diabetes? (0:22)
  2. Despite current treatment options, what unmet needs exist in the effective management of CKD in people with type 2 diabetes? (0:59)
  3. What is the mechanism of action of tirzepatide, and how does this differ from currently available therapies in this indication? (1:50)

Disclosures: Hiddo Heerspink is a consultant for: AstraZeneca, Bayer, Boehringer Ingelheim, Chinook, CSL Behring, Dimerix, Eli Lilly, Janssen, NovoNordisk and Travere. Hiddo Heerspink has received grant/research support from AstraZeneca, Boehringer Ingelheim and Novo Nordisk and is a speaker’s bureau participant with AstraZeneca.

Support: Interview and filming supported by Touch Medical Media. Interview conducted by Danielle Crosby.

Filmed as a highlight of ADA 2022.

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