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Saptarshi Bhattacharya, Sanjay Kalra, Lakshmi Nagendra

Very few trials in the history of medical science have altered the treatment landscape as profoundly as the UK Prospective Diabetes Study (UKPDS). Even 44 years after its inception, the trial and post-study follow-up findings continue to fascinate and enlighten the medical community. The study was conceived at a time when there was uncertainty about […]

Francisco Pasquel MD, MPH, ADA 2019 – The Glargine U300 Hospital Trial

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Published Online: Jun 19th 2019

We are joined by Professor Francisco Pasquel to discuss the findings, rationale and limitations of the Glargine U300 Hospital Trial, which is being presented at this year’s congress.

Filmed at the American Diabetes Association (ADA) annual meeting 2019, San Francisco, USA.

Questions:
1. What are the major challenges of managing hyperglycemia in the hospital setting? (0:05)
2. What is the rationale for the Glargine U300 Hospital Trial? (1:37)
3. What were the findings of the study? (2:26)
4. What are the limitations of Glargine U300? (2:58)
5. In which type 2 diabetes patients should Glargine U300 be considered and in which ones should it be avoided? (3:38)

Francisco Pasquel has received consulting fees and research support from Merck and consulting fees from Boehringer Ingelheim, Lilly, and AstraZeneca.

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