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Polycystic ovary syndrome (PCOS) is the most common endocrinopathy affecting women of reproductive age and is characterized by hyperandrogenism, anovulation and insulin resistance (IR).1 Women with PCOS have a high risk of developing type 2 diabetes (T2D), dyslipidaemia, hypertension and cardiovascular diseases.2,3 IR and hyperandrogenism are closely intertwined in the pathogenesis of PCOS. The current standard of […]

Barbora De Courten, ADA 2018 – Carnosine Supplementation in Diabetes Prevention

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Published Online: Jul 5th 2018

Barbora De Courten (Associate Professor at Monash University, Melbourne, Australia) discusses the latest studies into carnosine supplementation in diabetes prevention at ADA 2018. Carnosine is food supplement and has been shown in animal studies to prevent and be useful in the treatment of type 2 diabetes. It has been show to have anti-inflammatory, anti-oxidative, and anti-advanced glycation end product properties that are important mechanisms in type 2 diabetes and related diseases. The study presented at this meeting showed the effect of carnosine supplementation on cardiometabolic risk factors in obesity, prediabetes and diabetes.

Questions:
1. What is carnosine? (0:14)
2. What is the rationale behind its use in the prevention of diabetes? (0:35)
3. What are the key findings of your study around the effect of carnosine supplementation on cardiometabolic risk factors in obesity, prediabetes and diabetes? (1:21)
4. What are the key challenges in preventing diabetes? (1:49)

Filmed at ADA 2018, Orlando, FL, US

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