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Hyponatraemia is primarily a disorder of water balance or distribution, characterized by serum sodium (Nas) levels less than 135 mmol/L.1 Hyponatraemia is the most common electrolyte disorder among elderly patients and is associated with increased mortality rates and longer hospital stays.2–4 The syndrome of inappropriate antidiuretic hormone secretion (SIADH) is a frequent cause of hyponatraemia in […]

Barbora De Courten, ADA 2018 – Carnosine Supplementation in Diabetes Prevention

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Published Online: Jul 5th 2018

Barbora De Courten (Associate Professor at Monash University, Melbourne, Australia) discusses the latest studies into carnosine supplementation in diabetes prevention at ADA 2018. Carnosine is food supplement and has been shown in animal studies to prevent and be useful in the treatment of type 2 diabetes. It has been show to have anti-inflammatory, anti-oxidative, and anti-advanced glycation end product properties that are important mechanisms in type 2 diabetes and related diseases. The study presented at this meeting showed the effect of carnosine supplementation on cardiometabolic risk factors in obesity, prediabetes and diabetes.

Questions:
1. What is carnosine? (0:14)
2. What is the rationale behind its use in the prevention of diabetes? (0:35)
3. What are the key findings of your study around the effect of carnosine supplementation on cardiometabolic risk factors in obesity, prediabetes and diabetes? (1:21)
4. What are the key challenges in preventing diabetes? (1:49)

Filmed at ADA 2018, Orlando, FL, US

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