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Coronavirus disease 2019 (COVID-19) is a life-threatening infection caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).1 Diabetes mellitus is one of the most frequent comorbidities, related to hospitalization due to SARS-CoV-2 infection, as well as a risk factor for disease severity, poor disease outcome, increased morbidity and mortality rate.2–6 SARS-CoV-2 enters human cells by binding […]

Hertzel Gerstein, ADA 2022: The ELIXA biomarker study, protein biomarkers to identify cardiovascular outcomes in patients with type 2 diabetes and acute coronary syndrome

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Published Online: Jul 5th 2022

The ELIXA biomarker study evaluated protein biomarkers as clinical risk factors to identify people with type 2 diabetes and acute coronary syndrome who are at highest risk for cardiovascular (CV) outcomes and death. Professor Hertzel Gerstein (McMaster University, Hamilton, ON, Canada) discusses the outcomes of the ELIXA biomarker study and the implications of the findings for clinical practice.

The abstract entitled ‘Cardiovascular Outcomes in People with Type 2 Diabetes and Acute Coronary Syndrome—The ELIXA Biomarker Study was presented at the 82nd American Diabetes Association Scientific Session, June 3-7, 2022.

Questions

  1. Please can you describe the rationale for investigating novel protein biomarkers as risk factors for cardiovascular outcomes? (0:27)
  2. How did the ELIXA biomarker study evaluate potential novel protein risk factors and what were its key findings? (1:42)
  3. In your opinion, what are the implications of these results for clinical practice? (3:12)

Disclosures: Hertzel Gerstein is on the advisory board and a consultant for Sanofi. Hertzel Gerstein has received grant/research support and honorarium from Sanofi.

Support: Interview and filming supported by Touch Medical Media. Interview conducted by Danielle Crosby.

Filmed as a highlight of ADA 2022.

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