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We are pleased to present the latest issue of touchREVIEWS in Endocrinology, which offers a timely and thoughtprovoking collection of articles that reflect both the continuity and evolution of diabetes and metabolic disease research. In an era where technology, public health priorities and clinical paradigms are shifting rapidly, this issue highlights the importance of evidence-based […]

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Diabetes mellitus (DM) is a group of metabolic disorders marked by elevated blood glucose. It has many subtypes, including type 1 diabetes mellitus (T1DM), type 2 diabetes mellitus (T2DM), gestational diabetes and neonatal diabetes; of these, T1DM and T2...

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Welcome to the latest edition of touchREVIEWS in Endocrinology. In this edition we feature a range of review, case report and original research articles that highlight some key developments in our understanding and management of endocrinological disease. We start with ...

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The incidence of youth-onset type 2 diabetes (T2D) is increasing.1,2 Growing evidence has demonstrated that youth-onset T2D is rapidly progressive, with earlier onset of life-limiting complications compared with adult-onset T2D.3,4 Initiation of effective treatment that can restore beta ...

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Automated insulin delivery (AID) systems play an important role in the management of type 1 diabetes mellitus (T1DM) by helping users achieve the recommended glucose targets while reducing the episodes of hypoglycemia.1 First-generation AID systems, including MiniMed™ 630G (Medtronic, Dublin, ...

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Q. What are the major challenges of treating pediatric type 1 and 2 diabetes? Achieving optimal glycemic control in children and adolescents with diabetes remains a major challenge. Management of diabetes requires an age-specific approach, taking into account the needs and characteristics ...

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Diabetes is a worldwide health problem, and its prevalence is expected to rise in the coming years, not only in adults, but also in youth. The first stage is characterized by insulin resistance accompanied by a compensatory increase in insulin ...

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A cure for diabetes remains the ultimate aim for many diabetes researchers. Advances in closed loop/artificial pancreas (CL/AP) therapy and stem-cell research are bringing some hope for patients with type 1 diabetes. Better understanding of the nutrients effect on ...

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An avalanche is “a sudden arrival or occurrence of something in overwhelming quantities”.1 Is this an accurate description of the emerging complications seen in those with youth-onset type 2 diabetes? Type 2 diabetes of youth onset (diagnosed 12 years of age have developed ...

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The growing prevalence of obesity is a global health concern. In 2009 to 2010, more than one-third of adults and 17 % of youth in the US were obese, as defined by body mass index (BMI). Obesity is associated with numerous health risks such ...

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The hippocampus plays an important role in human learning and memory and is known to be vulnerable to the effects of stress and disease.1 Within animal models of type 1 diabetes,2 significant hyperglycemia and hypoglycemia exposure has been shown to cause ...

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The growing prevalence of obesity is a global health concern. In 2009 to 2010, more than one-third of adults and 17 % of youth in the US were obese, as defined by body mass index (BMI). Obesity is associated with numerous health risks such ...

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The hippocampus plays an important role in human learning and memory and is known to be vulnerable to the effects of stress and disease.1 Within animal models of type 1 diabetes,2 significant hyperglycemia and hypoglycemia exposure has been shown to cause ...

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Obesity has traditionally been defined as a body mass index (BMI) of 30 kg/m2 or more. However, BMI has limitations, and obesity is now defined by a number of factors, including waist circumference.1 The growing prevalence of obesity is a ...

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As a practicing pediatric endocrinologist in Los Angeles, California, I have witnessed significant changes over the past 30 years. During that time, there has not been a single week in which the Center for Diabetes at the Childrens Hospital Los Angeles ...

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Recent developments indicate that the efforts of diabetes teams who are implementing approaches focused on age-appropriate education of patients, families and other care-givers in intensified insulin treatment in paediatric diabetes care have been successful. Also, the increased availability of continuous ...

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Celebrated every year on November 14, World Diabetes Day is now an official UN World Health Day as a result of the successful Unite for Diabetes campaign. This year sees the second of a two-year World Diabetes Day campaign. The theme ...

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Treatment of Type 1 Diabetes in Children and Adolescents Treatment of Type 1 Diabetes in Children and AdolescentsDiabetes is one of the most common chronic conditions affecting children worldwide. Statistics gathered by the National Institutes of Health (NIH) in 2005 revealed that one ...

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As a practicing pediatric endocrinologist in Los Angeles, California, I have witnessed significant changes over the past 30 years. During that time, there has not been a single week in which the Center for Diabetes at the Childrens Hospital Los Angeles ...

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