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Thyroid gland inside human body. 3D illustration
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Thyroid eye disease (TED), also known as Graves’ orbitopathy, is a complex autoimmune disorder driven by an interplay of immune cells, orbital fibroblasts and tissue remodelling factors that lead to inflammation, oedema and, ultimately, potential vision loss.1 While the disease has historically been challenging to manage, recent therapeutic innovations are reshaping treatment paradigms and offering new […]

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What if your medical degree could launch more than a clinical career? In this candid and compelling read, Dr Jon Edelson shares his lessons for early-career clinicians ready to think beyond the bedside and explore the business of medicine.

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Dr Svenja Nölting shares how her international experiences and dedicated mentors shaped her career in neuroendocrine oncology, discusses the profound impact of hormones on the body, and highlights the future of precision medicine in tailoring treatments for endocrine disorders.

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Hypercalcaemia is a common clinical condition in hospitalized patients. Malignancies and primary hyperparathyroidism (PHPT) are the two most common causes of hypercalcaemia in hospitalized patients.1–3 Apparently, there is a changing profile of hypercalcaemia in India, especially in hospital settings, because ...

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Thyroid nodules are common worldwide, and their prevalence is increasing. Most nodules are asymptomatic and detected incidentally on cross-sectional imaging or physical examination. In rare cases (10–15%), nodules are malignant and require diagnostic evaluation. Even malignant nodules frequently show non-aggressive behaviour.1 ...

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Jose Paz-Ibarra, Marcio Concepción-Zavaleta, Juan Eduardo Quiroz-Aldave

Amyloid goiter (AG) is a benign condition characterized by the deposition of amorphous proteinaceous material in the thyroid gland to an extent that results in detectable enlargement during clinical evaluation.1–3 Amyloid can infiltrate the thyroid gland in 15–50% of individuals with ...

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Augusto Dextre-Espinoza, Sofía Pilar Ildefonso-Najarro, Marcio José Concepción-Zavaleta

Burkitt lymphoma (BL) is a non-Hodgkin B-cell lymphoma originating from the germinal center, characterized by dysregulation of the MYC gene, often resulting from the translocation of chromosome 8 into 14. It is extremely aggressive, representing the fastest proliferating cancer, and typically involves ...

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Evana Valenzuela-Scheker, David N Bimston, Hubert Golingan

In the USA, neck ultrasound (US) identifies thyroid nodules (TNs) in 30–50% of adult patients.1,2 Given that the risk of malignancy (ROM) for all combined thyroid nodule types ranges from 5% to 15%,2,3 current guidelines recommend US of the neck initially, to identify ...

37 mins
CE/CME accredited
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Prof. Brose explores how individual patient profiles underpin personalized medicine in thyroid cancer.

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Cornelius J Fernandez, Lakshmi Nagendra, Mohammed Alkhalifah

Hypertension affects up to 40% of the adult population worldwide,1 and according to the World Health Organization’s 2021 estimates, globally 1.28 billion adults between 18 and 79 years are affected.2 Of these, 85% have essential hypertension3 and the remainder have secondary hypertension, which is potentially ...

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Article highlights Lavender and tree tea oils have in vitro oestrogenic and antiandrogenic activity. It has been postulated that these oils may cause prepubertal gynaecomastia and premature thelarche. The association is based on a small number patients (N=12) described in ...

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Doaa Aboalola, Sihem Aouabdi, Majed Ramadan

Alopecia is a dermatological disorder characterized by hair loss from the scalp or body.1–3 It is one of the most common dermatological disorders worldwide and has several aetiologies, such as hereditary background, hormonal imbalance, infection or idiopathic causes.1,3,4 Alopecia can ...

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Parathyroid carcinoma is a rare endocrine neoplasm with an incidence of 0.5–2.0% of all cases of primary hyperparathyroidism (PHPT).1 It was first described in 1904 by de Quevain, when it was found in a patient presenting with a non-functioning parathyroid mass.2 Around 26 ...

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Coverage from: ENDO Highlights

Thyroid nodules arising in the isthmus are more likely to be malignant and demonstrate more aggressive behavior relative to thyroid nodules from either thyroid lobe. touchENDOCRINOLOGY were joined by Dr Sina Jasim (Washington University, St Louis, MO, USA) to discuss ...

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Coverage from: WCO-IOF-ESCEO Highlights

Primary hyperparathyroidism (PHPT) is caused by the overproduction of parathyroid hormone (PTH) by the parathyroid gland, the symptoms of which can remain dormant until later in life and as such PHPT is often underdiagnosed. We were delighted to speak to ...

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Coverage from: ATA Highlights

We caught up with the American Thyroid Association (ATA) president Prof. Julie Ann Sosa, MD, MA, FACS (University of California, San Francisco, CA, USA) ahead of this year’s virtual meeting to highlight their ATA Centennial Celebration at their upcoming ...

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Jose Paz-Ibarra, Marcio Concepción-Zavaleta, Daniel Mendoza-Quispe

Thyrolipomatosis is a rare condition defined as a diffuse non-neoplastic infiltration of fatty tissue in the thyroid gland.1 Although fatty infiltration is common in other glands (e.g. salivary glands, parathyroids, thymus and pancreas), it is rare in the thyroid ...

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Worldwide prevalence of type 2 diabetes mellitus (T2DM) is steadily increasing due to rising levels of obesity over the past 40 years caused by sedentary lifestyles and unhealthy eating habits. Diabetes now ranks ninth among the top ten causes of death ...

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New exciting therapies for neuroendocrine tumours include the introduction of RET inhibitors for medullary thyroid cancer and belzutifan for metastatic pancreatic neuroendocrine tumours. We were delighted to speak with our editorial board member Prof. Ashley Grossman (University of Oxford, Oxford, ...

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