Medullary Thyroid Cancer (MTC) is a rare cancer of the thyroid parafollicular or ‘C’ cells, and is estimated to make up around 5–10% of all thyroid cancers.1 MTC was first described in 1906 by Jacquet as a thyroid tumour with amyloid, but ...

Medullary Thyroid Cancer (MTC) is a rare cancer of the thyroid parafollicular or ‘C’ cells, and is estimated to make up around 5–10% of all thyroid cancers.1 MTC was first described in 1906 by Jacquet as a thyroid tumour with amyloid, but ...

Neuroendocrine tumours (NETs) represent a heterogeneous group of neoplasms that originate from different types of neuroendocrine cells throughout the body.1 While previously considered to be relatively uncommon, their overall incidence has been reported as increasing for reasons which are unclear.2–4 ...

Pituitary tumours are associated with pituitary dysfunction, either hypersecretion (mainly prolactinomas, acromegaly or Cushing’s disease [CD]) or hypopituitarism, due to compression or destruction of normal pituitary cells. They may also cause headache or visual disturbances due to pressure on ...

Thyroid cancer is the most common endocrine malignancy, being responsible for approximately 95 % of endocrine cases and 1.5 % of all cancers.1 Its incidence has increased substantially in recent decades and has been rising by 6.4 % per year over the past 10 years.1 This is ...

Neuroendocrine tumours (NETs) is a collective term for a diverse range of neoplasms that arise from cells that originate in the endocrine and nervous systems and share common morphological and immunohistochemical features, including the presence of secretory granules. These tumours ...

Acromegaly Epidemiology and Clinical Manifestations Acromegaly Epidemiology and Clinical Manifestations Acromegaly is an uncommon disorder characterised by the hypersecretion of growth hormone (GH) resulting in an increase in serum insulin-like growth factor-1 (IGF-1) levels. This condition is most often caused ...

Introduction Introduction Acromegaly is a rare disease and in majority of cases caused by a growth hormone (GH)-producing pituitary adenoma. More than 75 % of these adenomas are macroadenomas.1 Acromegaly is characterised by excessive skeletal growth, soft tissue enlargement and reduced ...

Introduction Introduction Acromegaly is a rare disease and in majority of cases caused by a growth hormone (GH)-producing pituitary adenoma. More than 75 % of these adenomas are macroadenomas.1 Acromegaly is characterised by excessive skeletal growth, soft tissue enlargement and reduced ...