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Diabetes is a chronic disease associated with both acute and chronic complications. Many advances have been introduced throughout history to address these problems. While each clinical breakthrough was welcomed with relief and the expectation that a solution had been discovered, ...
Article Highlights Early use of sodium–glucose co-transporter-2 inhibitors following myocardial infarction was associated with the following factors: Lower hospitalization for heart failure (odds ratio [OR]: 0.75; 95% confidence interval [CI]: 0.62–0.90; p=0.002). Similar cardiovascular deaths (OR: 1.04; 95% CI: 0.83–1.30; p=0.76). Similar all-cause mortality (OR: 1.00; 95% ...
New research has introduced a strategy that could considerably reduce the need for insulin therapy in patients with type 2 diabetes (T2D)
Dry eye disease (DED) is known as dry eye syndrome (DES) or keratoconjunctivitis sicca. According to the Tear Film and Ocular Surface Society’s Dry Eye Workshop II (TFOS DEWS II), it constitutes a multifactorial disease of the ocular surface, ...
Polycystic ovary syndrome (PCOS) is a multifactorial, multifaceted syndrome that affects women across all ages from adolescence to post-menopause. It is reported to be the most common endocrinopathy in women of the reproductive age group.1Â The nature of this syndrome ...
Despite the increasing body of knowledge of treatment strategies for diabetes, many patients with type 2 diabetes mellitus (T2DM) are still in a persistent state of poor glycaemia.1,2Â In clinical practice, achieving optimal glycaemic targets is challenging; the reasons are ...
Acromegaly is a chronic disease caused by an excess of growth hormone (GH) and insulin-like growth factor 1 (IGF-1).1,2Â Besides facial and acral changes, systemic complications lead to decreased quality of life and survival rates.3Â The primary goal of acromegaly treatment ...
Watch leading experts Prof. Moshe Phillip, Dr Sandro Loche and Prof. Antonio de Arriba discuss challenges in growth hormone disease management, and how digital health tools and data analytics can support HCPs and improve outcomes for patients.
Parathyroid carcinoma is a rare endocrine neoplasm with an incidence of 0.5–2.0% of all cases of primary hyperparathyroidism (PHPT).1 It was first described in 1904 by de Quevain, when it was found in a patient presenting with a non-functioning parathyroid mass.2 Around 26 ...
Diabetic foot ulcers are one of the major complications in patients with diabetes mellitus (DM). In one study, the global prevalence of diabetic foot ulcers was 6.3%, and the prevalence of diabetic foot ulcers differed between North America (13.0%) and Europe (5.1%).1 Besides ...
Insulin remains an important diabetes treatment, with 150–200 million people worldwide requiring insulin therapy.1 While insulin is vital for managing type 1 diabetes, basal insulin is typically recommended for type 2 diabetes when non-insulin therapies are not enough to achieve glycaemic targets.2 Several ...
Worldwide prevalence of type 2 diabetes mellitus (T2DM) is steadily increasing due to rising levels of obesity over the past 40 years caused by sedentary lifestyles and unhealthy eating habits. Diabetes now ranks ninth among the top ten causes of death ...
Chylomicronaemia refers to the pathological presence of large, circulating, intestinally derived chylomicrons.1 Clinical features of chylomicronaemia syndrome include lipaemic plasma, lipaemia retinalis, eruptive xanthomas, hepatosplenomegaly, neurological symptoms such as mental fog and mood changes and, most importantly, increased risk of ...
Nutrient-stimulated gastric inhibitory polypeptide (GIP) (known as either gastric inhibitory polypeptide or glucose-dependent insulinotropic polypeptide) or glucagon-like peptide (GLP-1), are secreted by K and L cells, respectively, in the upper segment of the small intestine and throughout the intestine. For ...
Obesity is a growing problem worldwide with extensive health and economic consequences, rendering interventions that encourage weight loss of great interest. Obesity is usually defined as a body mass index (BMI) of 30 kg/m2Â or above, or 27.5 kg/m2Â or ...
The World Health Organization (WHO) defines older adults as people aged 65 years or older.1Â Today, older adults with diabetes mellitus (DM) are a growing population, with 33% of older adults meeting the criteria for DM.2Â The risk of DM-related complications is ...
Craniopharyngiomas (CPs) are rare, benign, epithelial tumours of the sellar and parasellar regions arising as embryonic malformations along the pathway of the craniopharyngeal duct.1 They have an incidence of 0.13 per 100,000 per year to 0.5–2.0 per million per year and are classified ...
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