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Showing Results for leptin–melanocortin signalling pathway
Obesity defined as abnormal or excessive fat accumulation that presents a risk to health, is a chronic disease linked to metabolic co-morbidities, such as type 2 diabetes mellitus and cardiovascular disease, a reduced life expectancy, economic burden and reduced quality of ...
Ghrelin is a 28-amino-acid peptide predominantly secreted in the stomach and stimulates appetite and growth hormone (GH) release. The name ghrelin is based on ‘ghre’ a word root in Proto-Indo-European languages meaning ‘grow’ in reference to its ability to stimulate ...
Insulin in the Brain Insulin in the Brain Clinical Observations and Experimental Studies in Humans For a long time the brain was believed to be insensitive to the effects of insulin. However, 30 years ago it was shown that insulin and ...
The Natural History of Human Obesity The accumulation of body fat in obese people indicates the failure of the body’s systems to ensure proper energy homeostasis by adjusting for environmental influences, behaviour, psychological factors, genetic make-up and neurohormonal status.1 ...
Insulin in the Brain Insulin in the Brain Clinical Observations and Experimental Studies in Humans For a long time the brain was believed to be insensitive to the effects of insulin. However, 30 years ago it was shown that insulin and ...
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