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Thyroid gland inside human body. 3D illustration
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Thyroid eye disease (TED), also known as Graves’ orbitopathy, is a complex autoimmune disorder driven by an interplay of immune cells, orbital fibroblasts and tissue remodelling factors that lead to inflammation, oedema and, ultimately, potential vision loss.1 While the disease has historically been challenging to manage, recent therapeutic innovations are reshaping treatment paradigms and offering new […]

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María José Calvo, Heliana Parra, Raquel Santeliz

Gestational diabetes mellitus (GDM) is generally defined as “any degree of glucose tolerance with onset or first recognition during pregnancy”.1 It currently is one of the diseases with the highest morbidity among pregnant women.2 Determining its prevalence has been a ...

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Eleni Armeni, Ashley Grossman

Cushing’s disease (CD), or pituitary-dependent Cushing’s syndrome, is almost always caused by corticotroph tumours, a type of pituitary neuroendocrine tumour, which overproduces adrenocorticotrophic hormone (ACTH), ultimately leading to hypercortisolism and its associated clinical consequences, including increased mortality.1 The ...

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Primary hyperparathyroidism (PHPT) and cancer-related hypercalcaemia are the most common causes of hypercalcaemia and PHPT is the most common cause of hypercalcaemia in outpatients. An autonomous overproduction of parathyroid hormone (PTH) leading to hypercalcaemia, which is not downregulated by the ...

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According to the American Cancer Society, in 2013 there will be an estimated 1,660,290 new cancer cases and 580,350 deaths from cancer. Lung, colorectal, breast and prostate cancer are the most common malignancies in the US, accounting for approximately 50 % of new cancer diagnoses. ...

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