Polycystic ovary syndrome (PCOS) is a complex, multisystemic condition characterized by reproductive, metabolic and dermatologic manifestations, including hyperandrogenism and ovulatory dysfunction. Despite its prevalence and significant impact on quality of life, PCOS remains underdiagnosed and poorly managed due to its ...
Polycystic ovary syndrome (PCOS) is the most common endocrinopathy affecting women of reproductive age and is characterized by hyperandrogenism, anovulation and insulin resistance (IR).1Â Women with PCOS have a high risk of developing type 2 diabetes (T2D), dyslipidaemia, hypertension and ...
This systematic review and meta-analysis investigate the efficacy of teprotumumab, a novel monoclonal antibody, in reducing proptosis for patients with long-duration thyroid eye disease (TED). While teprotumumab has shown promise in treating active TED, its effectiveness in chronic cases remained ...
Alopecia is a dermatological disorder characterized by hair loss from the scalp or body.1–3 It is one of the most common dermatological disorders worldwide and has several aetiologies, such as hereditary background, hormonal imbalance, infection or idiopathic causes.1,3,4 Alopecia can ...
Postmenopausal state is associated with changes in the hormonal milieu characterized by reduced oestrogen, increased gonadotrophins and a small increase in testosterone levels.1,2Â As a result, it is not uncommon for women in postmenopausal age group to show mild increases ...
The role of testosterone is well established in health and disease.1Â Testosterone is known to mediate physical, mental and reproductive health. Its role has been discussed in gender-specific variations related to conditions as diverse as cardiovascular, autoimmune, psychiatric and oncological ...
Pituitary adenomas are benign tumours that arise from the adenohypophysis. They are the second most frequent intracranial tumour type after meningiomas, and account for 16.2% of all primary cranial neoplasms.1 Though likely an underestimate, the incidence of pituitary adenomas is approximately ...
Welcome to the latest edition of US Endocrinology, which includes a wide range of topical articles covering several areas of endocrinology, as well as being relevant to the broader biomedical community. We begin with three editorials on the increasingly important ...
Thyroid disease has commonly been associated with hair loss, predominantly manifesting as diffuse thinning of the scalp and the lateral eyebrows. This can be of particular concern to patients, and may motivate some to seek medical evaluation. Indeed, thyroid disease ...
Case presentation A 26-year-old woman with differentiated papillary thyroid carcinoma received 192 mCi of radioiodine 131 (I-131) under recombinant thyroidstimulating hormone (TSH) treatment for persistent upper mediastinal metastasis. Radioiodine whole-body scintigraphy (WBS) was performed nine days later and showed targeting of the ...
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in reproductive age women.1 According to National Institutes of Health (NIH) criteria (presence of ovulatory dysfunction and hyperandrogenism, after exclusion of related disorders), PCOS is estimated to affect 6–8% of women ...
Acromegaly Epidemiology and Clinical Manifestations Acromegaly Epidemiology and Clinical Manifestations Acromegaly is an uncommon disorder characterized by the hypersecretion of growth hormone (GH) resulting in an increase in serum insulin-like growth factor-1 (IGF-1) levels. This condition is most often caused ...
Testosterone therapy is of growing interest because of its increasingly recognized role in sexual and mental health, bone and muscle trophism, and vitality.1–4 An expanding body of evidence supports the influence of testosterone on sexuality, with the focus on desire ...
Testosterone therapy is of growing interest because of its increasingly recognized role in sexual and mental health, bone and muscle trophism, and vitality.1–4 An expanding body of evidence supports the influence of testosterone on sexuality, with the focus on desire ...
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