Adherence to medical regimen is often identified as a hallmark modifiable factor that impacts health outcomes for those with chronic medical illnesses.
Patients with type 2 diabetes commonly experience fatigue, which may be incapacitating and adversely affect self-care regimens.,sup>1–7 Fatigue is a perplexing problem for healthcare providers.8 Wessely suggests that because fatigue is a non-specific and universal symptom, chronic fatigue is challenging to diagnose and treat.9 Fatigue researchers do not have a standardised definition, measurement approach, or […]
Diabetes and ischemic stroke are common conditions that often co-occur. The relationship between diabetes and stroke is bidirectional.
The increased morbidity and mortality associated with diabetes are well known to health care providers. Retinopathy, nephropathy, macrovascular disease, neuropathy, and poor wound healing can have a major impact on the lives of patients with diabetes. These complications take an enormous personal and financial toll.
Diabetic nephropathy (DN) has become the most frequent cause of terminal renal failure in western countries. Its natural course has been well described and includes the development of functional and structural degenerative changes in the kidney. More specifically, glomerular membrane thickening, mesangial matrix expansion, microvascular changes, arteriolar hyalinosis, and tubular degeneration are characteristic aspects of […]
Cardiovascular disease (CVD) is the leading cause of mortality worldwide, and an overwhelming body of clinical evidence has demonstrated the efficacy of statin treatment in the prevention of this condition. Therapeutic goals in the prevention of CVD include management of dyslipidemia and of its complications such as hypertension and diabetes. Statins are the most widely […]
Pituitary tumors are common, with an estimated prevalence of 16.7 % in the general population based on imaging and autopsy studies.1 Clinically significant pituitary tumors are more prevalent than previously recognized, with one case per 1,000–1,300 people.2,3 The majority of pituitary tumors are indolent, slow-growing neoplasms.
The transition period is the span of time in which people complete their somatic and psychological development after reaching their full stature (also known as late teenage years, post-adolescence or young adulthood). It starts in late puberty and comes to an end at around 25 years of age, thus lasting from three to 10 years. […]
Malignancies of the thyroid can be classified as either of follicular cell origin or parafollicular C-cell origin.

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Highlights Autoantibodies refine autoimmune thyroid disorder diagnosis and risk. Thyroid-stimulating hormone receptor antibody predicts relapse, severity and foetal impact. Thyroid peroxidase antibody and thyroglobulin antibody linked to fertility outcomes. Novel antibodies expand thyroid autoimmunity scope. The interplay between immunology and endocrinology is vividly exemplified in autoimmune thyroid disorders (AITDs), where immune dysregulation targets the thyroid gland through both cellular and humoral mechanisms. Hashimoto’s thyroiditis […]
US Endocrinology is a peer-reviewed, free-to-access, bi-annual journal comprising review articles, case reports, editorials, special reports and original research. It features balanced and comprehensive articles written by leading authorities, addressing the most important and salient developments in the field of endocrinology.
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