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27 Results Found for “thyrotropin receptor”
Highlights Autoantibodies refine autoimmune thyroid disorder diagnosis and risk. Thyroid-stimulating hormone receptor antibody predicts relapse, severity and foetal impact. Thyroid peroxidase antibody and thyroglobulin antibody linked to fertility outcomes. Novel antibodies expand thyroid autoimmunity scope. The interplay between immunology and ...
This systematic review and meta-analysis investigate the efficacy of teprotumumab, a novel monoclonal antibody, in reducing proptosis for patients with long-duration thyroid eye disease (TED). While teprotumumab has shown promise in treating active TED, its effectiveness in chronic cases remained ...
Alopecia is a dermatological disorder characterized by hair loss from the scalp or body.1–3 It is one of the most common dermatological disorders worldwide and has several aetiologies, such as hereditary background, hormonal imbalance, infection or idiopathic causes.1,3,4 Alopecia can ...
Hypothyroidism usually presents with subtle signs and symptoms. Rarely, longstanding juvenile hypothyroidism can manifest as a syndromic diagnosis of Van Wyk–Grumbach syndrome (VWGS).1 VWGS presents as early menarche, thelarche, galactorrhoea, delayed bone ageing and multi-cystic ovaries, along with long-standing ...
Colloid goitre is defined as thyroid enlargement without accompanying disturbance in thyroid function. This is a common pathology, frequently found in clinical practice during a physical or ultrasound examination. Colloid goitre has been classified as nontoxic goitre according to the ...
Welcome to the summer edition of US Endocrinology. In this issue we present authoritative, up-to-date information on a wide range of salient topics. The pandemic of obesity is driving the diabetes epidemic across the globe, with developing countries especially bearing ...
In children, hyperthyroidism occurs less commonly compared to hypothyroidism, yet it is far more symptomatic.1 Hyperthyroidism in children is mostly due to autoimmunity, predominantly as a result of Graves’ disease.2 Non-autoimmune hyperthyroidism (NAH) is a rare cause of hyperthyroidism in ...
Pituitary adenomas are benign tumours that arise from the adenohypophysis. They are the second most frequent intracranial tumour type after meningiomas, and account for 16.2% of all primary cranial neoplasms.1 Though likely an underestimate, the incidence of pituitary adenomas is approximately ...
Adrenocortical carcinoma (ACC) is a rare endocrine tumour deriving from the adrenal cortex. Its estimated incidence is one per million/year,1 with an increased incidence in the first and fourth to fifth decades of life and with a higher prevalence ...
The year 2016 has been an exciting one in the world of thyroid disease, marking a new era for both research and clinical management. As a subspecialty, we are continuously re-evaluating not only our current treatment strategies, but also our classification ...
Thyroid nodules and thyroid cancers are more common in children than has been previously appreciated, and represent a significant health issue. Older studies used palpation to identify thyroid nodules and reported a childhood prevalence of 2%. However, high-resolution ultrasound identifies thyroid ...
Prolactinomas are the commonest pituitary tumours with a prevalence varying from 0.3 to 0.5 per 1,000 in the general population. This affection has a large female predominance and a median age of 30 years at diagnosis.1 Prolactinomas in men are characterised by a larger ...
Thyroid nodules are a common clinical problem and with the growing use of diagnostic imaging, the number of thyroid nodules identified and undergoing further diagnostic evaluation by fine-needle aspiration biopsy (FNA) is steadily growing. Only 5 % of all thyroid nodules harbour ...
Role of the Thyroid Hormones Role of the Thyroid Hormones Thyroid hormones play a vital role in the human body and, as such, the absence of such hormones requires treatment. Generally, levothyroxine is used to treat thyroid hormone deficiency, and ...
Thyroid nodules are a common clinical problem and with the growing use of diagnostic imaging, the number of thyroid nodules identified and undergoing further diagnostic evaluation by fine-needle aspiration biopsy (FNA) is steadily growing. Only 5 % of all thyroid nodules harbour ...
Prolactin Prolactin is a polypeptide hormone produced and secreted by the adenohypophysis. This hormone is in the family with growth hormone and human placental lactogen; in fact, they are sufficiently homologous to suggest a common ancestral gene. Prolactin Prolactin is ...
Prolactin Prolactin is a polypeptide hormone produced and secreted by the adenohypophysis. This hormone is in the family with growth hormone and human placental lactogen; in fact, they are sufficiently homologous to suggest a common ancestral gene. Prolactin Prolactin is ...
Prolactin (PRL) is a peptide hormone secreted by lactotroph cells of the anterior pituitary. PRL is predominantly under inhibitory influence of hypothalamic dopamine, whereas thyrotropin-releasing hormone (TRH), among other endogenous substances, is the main PRL-releasing factor. In physiological conditions, PRL ...
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