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39 Results Found for “thyroid peroxidase”
Highlights Autoantibodies refine autoimmune thyroid disorder diagnosis and risk. Thyroid-stimulating hormone receptor antibody predicts relapse, severity and foetal impact. Thyroid peroxidase antibody and thyroglobulin antibody linked to fertility outcomes. Novel antibodies expand thyroid autoimmunity scope. The interplay between immunology and ...
Thyrotoxicosis refers to the signs and symptoms derived from excess circulating thyroid hormones in the body,1 which must be differentiated from hyperthyroidism, in which there is an increase in the synthesis and secretion of hormones by the thyroid gland.2 Approximately 1% ...
The clinical presentation of hypocalcemia varies based on the degree and chronicity of the derangement. Although many patients remain asymptomatic, mild symptoms of hypocalcemia include circumoral and extremity paresthesia, Chvostek’s sign and Trousseau’s sign; more severe derangements can ...
Immune checkpoints are small molecules that are present on the cell surface of T lymphocytes to regulate the immune response. While some of these molecules enhance the stimulatory signals, others boost the inhibitory signals to blunt the activity of T ...
Hyperthyroidism is associated with neurological symptoms, such as tremor and muscle weakness, but chorea is rare and occurs in less than 2% of patients.1 Chorea is rarely seen at presentation in Graves’ disease, and more commonly occurs with streptococcal infection. Acute ...
The estimation of lipid parameters has traditionally been carried out in the fasting state, without definitive evidence to suggest that this is superior to assessing them in the post-prandial period in terms of predicting metabolic outcomes and cardiovascular risk.1 Post-prandial ...
Insulin autoimmune syndrome (IAS) is a leading cause of hypoglycaemia in the Japanese population.1 In India, which has a population of more than 1 billion, only 28 cases of IAS have been reported to date, to the best of our knowledge.2–10 IAS ...
Polycystic ovary syndrome (PCOS), the most common endocrine disorder in women of reproductive age, is a heterogeneous androgen-excess disorder with different degrees of reproductive and metabolic dysfunctions.1 Thyroid disorders are also quite common and are among the most common endocrine ...
In children, hyperthyroidism occurs less commonly compared to hypothyroidism, yet it is far more symptomatic.1 Hyperthyroidism in children is mostly due to autoimmunity, predominantly as a result of Graves’ disease.2 Non-autoimmune hyperthyroidism (NAH) is a rare cause of hyperthyroidism in ...
The armamentarium of anticancer drugs available to an oncologist has grown rapidly over the past few decades. The use of cancer immunotherapy and targeted therapy has become more popular in the last few years. It has also become increasingly clear ...
This interview explores current controversies in the management of hypothyroidism in children. Newborn screening programs have allowed early detection and treatment of babies with congenital hypothyroidism, but some programs do not detect cases with delayed thyroid-stimulating hormone (TSH) elevation ...
Thyroid disease has commonly been associated with hair loss, predominantly manifesting as diffuse thinning of the scalp and the lateral eyebrows. This can be of particular concern to patients, and may motivate some to seek medical evaluation. Indeed, thyroid disease ...
The human foetus is capable of producing thyroid hormones at around 20 weeks of gestation. Even in the rare event that there happens to be a defect in thyroid organogenesis or an inborn error in thyroid hormone synthesis, the developing foetal ...
Thyroid nodules and thyroid cancers are more common in children than has been previously appreciated, and represent a significant health issue. Older studies used palpation to identify thyroid nodules and reported a childhood prevalence of 2%. However, high-resolution ultrasound identifies thyroid ...
The autoimmune thyroid diseases (AITD) comprise a series of interrelated conditions including Graves’ disease (GD) and Hashimoto’s thyroiditis (HT). AITD are the most prevalent diseases of the thyroid gland in the pediatric population, particularly in adolescence.1 HT is the ...
The steadily increasing knowledge concerning selenium (Se) involvement in chronic autoimmune and viral inflammatory disease along with the growing prospect of preventive and/or therapeutic Se intervention, via diet or compounds, are the focus of this brief review. Important data ...
Moyamoya is a rare idiopathic cerebral vasculopathy characterized by stenosis of the terminal portion of the internal carotid arteries (ICAs) and the development of a thin collateral network of small vessels (“puff of smoke”), initially described as a primary disease ...
The autoimmune thyroid diseases (AITD) comprise a series of interrelated conditions including Graves’ disease (GD) and Hashimoto’s thyroiditis (HT). AITD are the most prevalent diseases of the thyroid gland in the pediatric population, particularly in adolescence.1 HT is the ...
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