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44 Results Found for “thyroglobulin”
Highlights Autoantibodies refine autoimmune thyroid disorder diagnosis and risk. Thyroid-stimulating hormone receptor antibody predicts relapse, severity and foetal impact. Thyroid peroxidase antibody and thyroglobulin antibody linked to fertility outcomes. Novel antibodies expand thyroid autoimmunity scope. The interplay between immunology and ...
The LEVOLIO study was a randomized double-blind placebo-controlled trial on levothyroxine and liothyronine combination therapy for hypothryroidism. touchENDOCRINOLOGY were delighted to speak with Dr Giulia Brigante (University of Modena and Reggio Emilia, Modena, Italy) about the data from the LEVOLIO ...
Clinicians depend on accurate, precise and reproducible hormone measurements for the diagnosis and management of endocrine disorders. Immunoassays have constituted one of the major methods of measuring hormone levels in blood, urine and other fluids, as well as in tissue ...
Immune checkpoints are small molecules that are present on the cell surface of T lymphocytes to regulate the immune response. While some of these molecules enhance the stimulatory signals, others boost the inhibitory signals to blunt the activity of T ...
Hyperthyroidism is associated with neurological symptoms, such as tremor and muscle weakness, but chorea is rare and occurs in less than 2% of patients.1 Chorea is rarely seen at presentation in Graves’ disease, and more commonly occurs with streptococcal infection. Acute ...
In children, hyperthyroidism occurs less commonly compared to hypothyroidism, yet it is far more symptomatic.1 Hyperthyroidism in children is mostly due to autoimmunity, predominantly as a result of Graves’ disease.2 Non-autoimmune hyperthyroidism (NAH) is a rare cause of hyperthyroidism in ...
Liquid biopsy is a rapidly emerging technique that measures extracellular DNA in a patient’s blood and is of considerable interest as a non-invasive method for early recognition and management of cancer.1,2 Circulating cell-free DNA (cfDNA) fragments in the blood ...
Malignancies of the thyroid are one of the most common neoplasms and predominantly affect females. Differentiated thyroid carcinomas include papillary and follicular carcinomas (accounting for 90–95% of all cases).1 Papillary carcinoma is the most common type of all thyroid malignancies, while ...
This interview explores current controversies in the management of hypothyroidism in children. Newborn screening programs have allowed early detection and treatment of babies with congenital hypothyroidism, but some programs do not detect cases with delayed thyroid-stimulating hormone (TSH) elevation ...
Many recent publications have increased our knowledge on several aspects of thyroid carcinoma, namely on the molecular mechanisms involved in the initiation and progression of neoplasias, on the clinical and histopathological evaluation of patients and tumour samples and on the ...
Thyroid carcinoma is one of the most common solid tumors worldwide. The incidence of thyroid cancer is increasing, with an estimated 57,000 newly diagnosed cases in the US in 2017. Approximately three-quarters of these patients are female, with the majority being between 20 ...
Case presentation A 32-year-old woman presented to our clinic while three months pregnant, with a left-sided neck mass that she had felt about 10 months prior to presentation. She noticed that the mass had grown slightly over that period. She denied ...
Subclinical hypothyroidism (SH), sometimes referred to as mild hypothyroidism, is a cumbersome term used to describe the compensatory increase in thyroid-stimulating hormone (TSH) levels to preserve normal thyroid hormone levels before they fall below normal, thus averting thyroid gland failure. ...
The year 2016 has been an exciting one in the world of thyroid disease, marking a new era for both research and clinical management. As a subspecialty, we are continuously re-evaluating not only our current treatment strategies, but also our classification ...
Subclinical hypothyroidism (SH), sometimes referred to as mild hypothyroidism, is a cumbersome term used to describe the compensatory increase in thyroid-stimulating hormone (TSH) levels to preserve normal thyroid hormone levels before they fall below normal, thus averting thyroid gland failure. ...
The human foetus is capable of producing thyroid hormones at around 20 weeks of gestation. Even in the rare event that there happens to be a defect in thyroid organogenesis or an inborn error in thyroid hormone synthesis, the developing foetal ...
Thyroid nodules and thyroid cancers are more common in children than has been previously appreciated, and represent a significant health issue. Older studies used palpation to identify thyroid nodules and reported a childhood prevalence of 2%. However, high-resolution ultrasound identifies thyroid ...
Case presentation A 26-year-old woman with differentiated papillary thyroid carcinoma received 192 mCi of radioiodine 131 (I-131) under recombinant thyroidstimulating hormone (TSH) treatment for persistent upper mediastinal metastasis. Radioiodine whole-body scintigraphy (WBS) was performed nine days later and showed targeting of the ...
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