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In response to the increasing prevalence of obesity, the consumption of high-calorie and high-sugar foods and an unprecedented aging population, type 2 diabetes (T2D) continues to rise globally. The International Diabetes Federation reported that 589 million individuals aged 20 to 79 years had been diagnosed with diabetes by the end of 2024.1 The world prevalence of diabetes […]

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81 Results Found for “peripheral neuropathy”

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health wellness Glowing red nerve lines spreading from feet on dark gradient background symbolizing diabetic neuropathy pain and discomfort nerve damage illustration
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Marcio J Concepción-Zavaleta, Jenyfer Maria Fuentes-Mendoza, Luis Concepción-Urteaga

Peripheral neuropathy is a common and clinically heterogeneous condition resulting from damage to the peripheral nervous system, affecting sensory, motor and autonomic fibers.1 Its diagnostic complexity stems from a broad spectrum of etiologies, including metabolic, autoimmune, infectious, toxic, neoplastic and ...

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As touchENDOCRINOLOGY approaches 22 years of providing education for busy endocrinologists, we are looking to the future—and it certainly looks bright! This year, we are celebrating our inaugural touchENDOCRINOLOGY Future Leaders to recognize the outstanding talent that has entered our ...

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In this Future Leader Q&A, Dr Gordon Sloan discusses his journey into diabetes and endocrinology, his research on diabetic peripheral neuropathy, and how mentorship, scientific curiosity and patient impact are driving his mission to improve outcomes for people living with this under-recognized complication of diabetes.

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Sanjay Kalra, Nikhil Sharad Gokhale, Ganapathi Bantwal

Dry eye disease (DED) is known as dry eye syndrome (DES) or keratoconjunctivitis sicca. According to the Tear Film and Ocular Surface Society’s Dry Eye Workshop II (TFOS DEWS II), it constitutes a multifactorial disease of the ocular surface, ...

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touchENDOCRINOLOGY was delighted to speak with Editorial Board member Dr Deep Dutta, a senior endocrinologist at the CEDAR Superspecialty Clinics, New Delhi, India. Throughout this interview, he summarizes the key messages from his late-breaking abstract session ‘Ailing Heart, Broken Vessels’, presented at the 60th European Association for the Study of Diabetes (EASD) annual meeting in Madrid, Spain.

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Metformin Metformin has been recommended as the first-line glucose-lowering agent for the management of type 2 diabetes (T2D) for several decades due to its efficacy and safety profile.1–3 In fact, metformin has been widely used as an insulin-sensitizing agent for ...

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Juan Miguel Huertas Cañas, Maria Alejandra Gomez Gutierrez, Andres Bedoya Ossa

The incidence of diabetes has increased in recent years, and advances in technology have allowed for multiple ways to predict the outcomes of patients with diabetes, and have improved quality of life and lowered morbidity and mortality.1 For decades, glycated ...

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Type 2 diabetes (T2DM) is a disease with a complex aetiopathogenesis that leads to a wide variety of metabolic disorders. This includes, by definition, high plasma glucose levels, but also elevated blood pressure, dyslipidaemia, cardiorenal complications and strokes. All of ...

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Diabetic foot ulcers are one of the major complications in patients with diabetes mellitus (DM). In one study, the global prevalence of diabetic foot ulcers was 6.3%, and the prevalence of diabetic foot ulcers differed between North America (13.0%) and Europe (5.1%).1 Besides ...

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Article highlights Epigenetics refers to the heritable changes in DNA expression without changes in the genetic code. Epigenetic changes are brought about by post-translational modifications of histone proteins, covalent modifications of DNA bases and microRNA. Epigenetics explains how environmental milieu ...

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For people with type 1 diabetes mellitus (T1DM) or type 2 diabetes mellitus (T2DM), glycaemic control has been monitored by two key measurements: laboratory-tested glycated haemoglobin (HbA1c) level and the individuals’ self-monitored blood glucose (SMBG) fingerprick testing.1,2 Both of ...

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The pandemic of type 2 diabetes mellitus (T2D) is a growing concern, especially in low- and middle-income countries, which contribute to nearly 75% of the disease burden.1 Indian patients with T2D constitute 1 in 6 adults with T2D globally, with marked ...

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Long-chain fatty-acid oxidation disorders (LC-FAODs) are pan-ethnic, autosomal recessive, inherited metabolic conditions causing disruption in the processing or transportation of fats into the mitochondria to perform beta oxidation.1 In normal metabolism, long-chain fatty acids are bound to carnitine within the ...

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Immune checkpoints are small molecules that are present on the cell surface of T lymphocytes to regulate the immune response. While some of these molecules enhance the stimulatory signals, others boost the inhibitory signals to blunt the activity of T ...

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John Doupis, Konstantinos Karras, Konstantinos Avramidis

Diabetes mellitus is a chronic disease that affects many people around the world. Sedentary lifestyle is considered a main risk factor for type 2 diabetes mellitus (T2DM). As presented in this editorial, the advantages of activity in preventing and treating ...

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Aishwarya Krishnamurthy, Saptarshi Bhattacharya, Tejal Lathia

Recent advances have bolstered the anticancer therapeutic armamentarium. However, despite the enhanced efficacy and better survival offered by these newer agents, side effects remain a source of concern.1 Gastrointestinal side effects, organ toxicities and dyselectrolytaemias are critical adverse consequences. Among ...

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Diabetic polyneuropathy (DPN) is the most common microvascular complication of diabetes, affecting approximately 50% of all people with diabetes (type 1 diabetes [T1D] and type 2 diabetes [T2D]).1 DPN is a major cause of disability due to sensory loss, gait instability ...

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India has a vast diversity of cultures and religions following a vast number of festivals and rituals irrespective of their caste, creed, age, and status with different rituals.1 The Hindu religion constitutes the world’s third largest religion and 80% of ...

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