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In response to the increasing prevalence of obesity, the consumption of high-calorie and high-sugar foods and an unprecedented aging population, type 2 diabetes (T2D) continues to rise globally. The International Diabetes Federation reported that 589 million individuals aged 20 to 79 years had been diagnosed with diabetes by the end of 2024.1 The world prevalence of diabetes […]

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Welcome to the summer 2026 issue of touchREVIEWS in Endocrinology. In this issue, we bring together articles that reflect the evolving complexity of endocrine and metabolic disease, while highlighting the growing importance of patient-centred care, translational science and interdisciplinary management. We ...

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Pathophysiology of X-linked hypophosphataemia X-linked hypophosphataemia (XLH) is a progressive skeletal disorder, originally defined by Albright in 1937 as hypophosphataemic vitamin D rickets.1 XLH is the commonest form of inherited rickets/osteomalacia and is an X-linked dominant condition.2 The most common ...

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Hiya Boro, Saurav Khatiwada, Sarah Alam

Renal tubular acidosis (RTA) is characterized by the impaired ability of the kidneys to absorb filtered bicarbonate or to excrete titrable acid in urine.1 It manifests as normal anion gap (hyperchloremic) metabolic acidosis. RTA may be of four types: type 1 (...

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Martin J Rutkowski, Derek G Southwell, Tyler M Cardinal

McCune–Albright syndrome (MAS) is a genetic disorder first described by McCune1 and Albright2  in the 1930s as a triad of polyostotic fibrous dysplasia, café-au-lait spots, and precocious puberty (Figure 1). Since then, other hyperfunctioning endocrinopathies have been described in ...

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  Disorders related to bone health are commonly seen in clinical practice in India. The most common conditions are vitamin D deficiency-related disorders (rickets, osteomalacia), followed by osteoporosis, hyperparathyroidism, endocrine osteopathies, and impaired bone health associated with systemic diseases.1–3 Vitamin ...

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Welcome to the latest edition of European Endocrinology, which features a range of insightful articles covering several areas of endocrinology. In recent years, a key requirement of clinical trials investigating new antidiabetes agents has been to demonstrate cardiovascular safety. An ...

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Oncogenic osteomalcia, also known as tumour-induced osteomalacia (TIO), is a rare paraneoplasatic syndrome with around 350 reported cases.1 TIO initial symptoms are nonspecific and include fatigue, bone pain, muscle weakness, weight, and height loss, and later bone deformity and fractures. It ...

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The advent of highly active anti-retroviral therapy (HAART) has significantly improved the survival of human immunodeficiency virus (HIV)-infected patients.1 In this context, HIV-infected patients are living longer and are facing several associated morbidities related with ageing, such as diabetes, ...

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Hypovitaminosis D and Obesity – Coincidence or Consequence? Nowadays the number of studies involving vitamin D and its interaction with metabolism have grown and gained great exposure in the scientific literature. The main reason for this is the high incidence of ...

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Hypovitaminosis D and Obesity— Coincidence or Consequence? Nowadays the number of studies involving vitamin D and its interaction with metabolism have grown and gained great exposure in the scientific literature. The main reason for this is the high incidence of ...

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At the outset, it is important to understand that the 2011 Institute of Medicine (IOM) recommendations for vitamin D1,2 can be taken at three levels of applicability. The first is the level of my own decision, for my own intake, informed ...

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At the outset, it is important to understand that the 2011 Institute of Medicine (IOM) recommendations for vitamin D1,2 can be taken at three levels of applicability. The first is the level of my own decision, for my own intake, informed ...

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The advent of highly active anti-retroviral therapy (HAART) has significantly improved the survival of human immunodeficiency virus (HIV)-infected patients.1 In this context, HIV-infected patients are living longer and are facing several associated morbidities related with ageing, such as diabetes, ...

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