Urinary lithogenesis processes are activated in patients with obesity, metabolic syndrome (MetS), and type 2 diabetes (T2D). This is a relatively unfamiliar topic among endocrinologists. Beyond the epidemiological evidence accumulated over the recent years, the purpose of this paper is ...

Parathyroid carcinoma is a rare endocrine neoplasm with an incidence of 0.5–2.0% of all cases of primary hyperparathyroidism (PHPT).1 It was first described in 1904 by de Quevain, when it was found in a patient presenting with a non-functioning parathyroid mass.2 Around 26 ...

Renal tubular acidosis (RTA) is characterized by the impaired ability of the kidneys to absorb filtered bicarbonate or to excrete titrable acid in urine.1 It manifests as normal anion gap (hyperchloremic) metabolic acidosis. RTA may be of four types: type 1 (...

  Ketogenic diet (KD) is defined as a high-fat, low-carbohydrate diet, with adequate protein content, which makes the body utilize fat, rather than carbohydrate, as a preferred energy substrate. In a carbohydrate-replete person, this substrate is converted to glucose, which ...

  Disorders related to bone health are commonly seen in clinical practice in India. The most common conditions are vitamin D deficiency-related disorders (rickets, osteomalacia), followed by osteoporosis, hyperparathyroidism, endocrine osteopathies, and impaired bone health associated with systemic diseases.1–3 Vitamin ...

According to the estimates of the International Diabetes Federation (IDF), one in every 11 adults of the global population has diabetes, with an overall disease prevalence of 425 million.1 This diabetes prevalence is expected to increase exponentially with time because of the ...

Chronic kidney disease (CKD), a condition that affects up to a third of patients who have diabetes, is a major public health problem in the US.1 There is a high level of interindividual variability in the rate of CKD progression, ...

Summary An interesting case of persistent hypercalcaemia of primary hyperparathyroidism (pHPT) resistant to medical management for more than 5 years, who demonstrated a dramatic response to the first dose of denosumab with a significant and persistent drop in her level of ...

Primary Hyperparathyroidism – An Evolving Disorder Primary Hyperparathyroidism – An Evolving Disorder Primary hyperparathyroidism (HPT) is a common endocrine disease characterised by inappropriately high serum levels of parathyroid hormone (PTH) and elevated calcium.Indeed, it is the leading cause of hypercalcaemia in ...