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124 Results Found for “hypothyroidism”
Hyperprolactinemia is a frequent cause for medical referrals to endocrinology departments. Markedly elevated prolactin levels are generally indicative of macroprolactinomas, whereas mild to moderate hyperprolactinemia may arise from physiological factors (such as exercise, sleep or stress), pharmacological agents, metabolic disturbances, ...
Peripheral neuropathy is a common and clinically heterogeneous condition resulting from damage to the peripheral nervous system, affecting sensory, motor and autonomic fibers.1 Its diagnostic complexity stems from a broad spectrum of etiologies, including metabolic, autoimmune, infectious, toxic, neoplastic and ...
Highlights Autoantibodies refine autoimmune thyroid disorder diagnosis and risk. Thyroid-stimulating hormone receptor antibody predicts relapse, severity and foetal impact. Thyroid peroxidase antibody and thyroglobulin antibody linked to fertility outcomes. Novel antibodies expand thyroid autoimmunity scope. The interplay between immunology and ...
The growing convergence of type 2 diabetes (T2D), obesity and dementia represents a pressing public health challenge in ageing populations worldwide.1 Robust epidemiological studies and meta-analyses have consistently shown that T2D is associated with accelerated cognitive decline.1,2 Beyond statistical ...
Hyponatraemia is primarily a disorder of water balance or distribution, characterized by serum sodium (Nas) levels less than 135 mmol/L.1 Hyponatraemia is the most common electrolyte disorder among elderly patients and is associated with increased mortality rates and longer hospital ...
The prevalence of diabetes during pregnancy is rapidly increasing. In the USA alone, an estimated 1–2% of pregnant women have type 1 diabetes (T1D) or type 2 diabetes (T2D), and an additional 6–9% develop gestational diabetes.1 From 2000 to 2010, the prevalence of gestational ...
Obesity defined as abnormal or excessive fat accumulation that presents a risk to health, is a chronic disease linked to metabolic co-morbidities, such as type 2 diabetes mellitus and cardiovascular disease, a reduced life expectancy, economic burden and reduced quality of ...
Burkitt lymphoma (BL) is a non-Hodgkin B-cell lymphoma originating from the germinal center, characterized by dysregulation of the MYC gene, often resulting from the translocation of chromosome 8 into 14. It is extremely aggressive, representing the fastest proliferating cancer, and typically involves ...
Article highlights Lavender and tree tea oils have in vitro oestrogenic and antiandrogenic activity. It has been postulated that these oils may cause prepubertal gynaecomastia and premature thelarche. The association is based on a small number patients (N=12) described in ...
Alopecia is a dermatological disorder characterized by hair loss from the scalp or body.1–3 It is one of the most common dermatological disorders worldwide and has several aetiologies, such as hereditary background, hormonal imbalance, infection or idiopathic causes.1,3,4 Alopecia can ...
The LEVOLIO study was a randomized double-blind placebo-controlled trial on levothyroxine and liothyronine combination therapy for hypothryroidism. touchENDOCRINOLOGY were delighted to speak with Dr Giulia Brigante (University of Modena and Reggio Emilia, Modena, Italy) about the data from the LEVOLIO ...
Hypothryroidism is a is a chronic condition in which you have an underactive thyroid where it does not produce enough thyroid hormones. touchENDOCRINOLOGY were delighted to speak with Dr Giulia Brigante (University of Modena and Reggio Emilia, Modena, Italy) about ...
Welcome to the latest edition of touchREVIEWS in Endocrinology. In this edition we feature a range of review, case report and original research articles that highlight some key developments in our understanding and management of endocrinological disease. We start with ...
Non-alcoholic fatty liver disease (NAFLD) encompasses a spectrum of fatty liver diseases, including non-alcoholic fatty liver (NAFL) and non-alcoholic steatohepatitis (NASH).1 NAFLD is associated with metabolic disorders, including obesity, hypertension, dyslipidaemia, type 2 diabetes mellitus (T2DM), hypothyroidism and metabolic syndrome.2 ...
Hypothyroidism usually presents with subtle signs and symptoms. Rarely, longstanding juvenile hypothyroidism can manifest as a syndromic diagnosis of Van Wyk–Grumbach syndrome (VWGS).1 VWGS presents as early menarche, thelarche, galactorrhoea, delayed bone ageing and multi-cystic ovaries, along with long-standing ...
There has also been high interest in the treatment of hypothyroidism in older adults, the treatment of thyroid eye disease and the increase of radiofrequency ablation for thyroid nodules to reduce their size by 50% to 97%. We were delighted to speak ...
Non-alcoholic fatty liver disease (NAFLD), which impacts an estimated 25% of the world’s adult population,1–3 is the principal cause of chronic liver disease globally. NAFLD as a whole represents a pathological spectrum of liver injury, spanning from simple steatosis to ...
In the early 1970s, the discovery of statin by Dr Akira Endo changed the fate of cardiovascular disease prevention and the treatment of atherosclerosis. It was during this period that the rate-limiting step in cholesterol biosynthesis was revealed, and the ...
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